What should be monitored to prevent cumulative effects of medication?

To prevent cumulative effects of medication, it's critical to monitor the frequency of administration. Cumulative effects occur when a drug is administered repeatedly without allowing the body enough time to fully metabolize or eliminate it. By keeping track of how often the medication is being given, healthcare providers can adjust dosages or frequencies accordingly to ensure that the drug does not build up to dangerous levels in the body.

Considering the other options, simply reviewing the initial dose does not account for subsequent doses that could contribute to cumulative effects over time. A thorough understanding of drug interactions is important for overall medication safety, but it does not specifically target the issue of administration frequency that leads to accumulation. Labeling of medications is necessary for proper identification and use, but it does not inherently ensure that the cumulative effects are being accounted for. Monitoring administration frequency is a proactive approach to ensure patient safety and manage potential risks associated with medication metabolism and elimination.